Researchers at the
Center for Cellular Therapy, University of São Paulo (USP), Ribeirão Preto (SP
- Brazil) identified one of the genes responsible for the activation of cells
responsible for metastasis - the process in which cancer spreads through the body
via the bloodstream. Hotair known as the gene triggers a mechanism which
transforms the
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| UNIVERSIDADE DE SAO PAULO (USP) - BRAZIL |
mesenchymal cancer cells - with the ability to exit the site of
origin and lodge in other organs. With the discovery, recently published in
scientific journals such as the American Stem Cells, researchers believe it is
possible to inhibit the future, the action of genes and maintain localized
cancer, which would facilitate the healing of disease.
According to the
professor of genetics and a researcher Wilson Araújo Silva Júnior, were three
years of research to identify which genes might be involved with the
development of tumors . The relation to the hotair cancer was already known ,
but its function expansion was evident in the study . "We have important
information , which is to show that the hotair is one of the genes that are
involved in the activation of metastasis . Already it is known that metastasis
is a stage in the evolution of the tumor makes it difficult to control the
cancer. Already knew that the hotair is a gene that is highly active in
metastatic tissues . what we did not know was that he is one of the genes that
was triggering metastasis , " he explains.
Smith Jr. states that
the hotair , as a gene that produces protein has the ability to regulate the
expression of other genes. Thus, it is known that other genes regulated by it
are also responsible for the activation of the process of metastasis. "
The hotair is an important component to activate metastasis , it is an RNA gene
. What it does is regulate the activation of other genes , which indeed are
involved in metastasis," he says.
The next step of the
study , according to the researcher , is identify which genes controlled by
hotair who are also involved in the activation of metastasis . The goal is that
in the future you can find a way to inhibit the action of these genes , so keep
cancer is located in only one area .
" This discovery is not a cure for cancer ,
but it is an element that , with others, can serve as a tool for pharmaceutical
companies to develop drugs to control the tumor. Controlling the action of this
gene, is automatically controls the action of genes that it regulates . Here
you have, in theory , control the spread of the tumor. This is already a
breakthrough. By controlling metastasis , you hold the localized tumor ,
"he concludes .
SOURCE: GLOBO.COM
This is the thinking of all Brazilian people, since they have the biggest defeat of their lives.
The fans are shamed and sad, because the euphoric feeling had just finish, not with a single normal loss, like 1 x 0 or 2 x 1, but believe or not: 7 x 1 !!!
